|
Symbol Name ID |
Flt1
FMS-like tyrosine kinase 1 MGI:95558 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Elevated diastolic blood pressure |
Elevated systolic blood pressure |
Hypertension |
Abnormality of the hepatic vasculature |
Hepatosplenomegaly |
| Disease(s) Associated with FLT1 | |||||
| pre-eclampsia |
| Mouse Phenotypes | cardiovascular system phenotype |
abnormal blood vessel morphology |
abnormal dorsal aorta morphology |
abnormal vascular endothelial cell morphology |
abnormal vascular development |
abnormal physiological neovascularization |
increased angiogenesis |
abnormal vitelline vasculature morphology |
disorganized yolk sac vascular plexus |
abnormal heart development |
abnormal blood circulation |
increased response of heart to induced stress |
decreased myocardial infarct size |
increased vascular permeability |
cornea vascularization |
|
| Availability | Mouse Genotype | |||||||||||||||
| Flt1tm1Gne/Flt1tm1Gne | ||||||||||||||||
| Flt1tm1Jrt/Flt1tm1Jrt | ||||||||||||||||
| Flt1tm1Msh/Flt1tm1Msh | * | |||||||||||||||
| Flt1tm2Msh/Flt1tm2Msh | ||||||||||||||||
| Flt1tm1Jrt/Flt1+ | ||||||||||||||||
| Flt1tm1Jrt/Flt1tm1.2Fong | ||||||||||||||||
| Flt1tm1.1Fong/Flt1tm1.1Fong Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+ (conditional) |
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| Flt1tm1Eze/Flt1tm1Eze Tg(Prrx1-cre)1Cjt/0 (conditional) |
* | |||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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